Quirks and details

There are additional details that are not commonly asked but it is important to retain on record. This is a compendium of those.

  • Source 1 and 9 use larger plates (1536 vs the standard 384)
  • Source 7 and 13 are the same
  • In JUMP-Target there is an InChIKey that maps to 2 different perturbations: ‘LOUPRKONTZGTKE-UHFFFAOYSA-N’ maps to both quinidine and quinine.
  • The definition of controls, specially positive controls, can be tricky: Some are hard-coded in broad_babel, based on internal knowledge that was not recorded at the time of assembling the datasets. In certain datasets, such as ORF, there are additional types of positive controls: poscon_orf, poscon_cp (compound probe), and poscon_diverse.